Adult Obesity May Result From Genetic Variations In Childhood

A number of genetic variants linked to the risk of obesity in adults may start showing early in life, according to a new study by British and Finnish researchers that may help find better ways to prevent obesity.


Body mass index (bmi) tends to rise rapidly after birth and does not begin to decline until nine months of age, when it remains at about five to six years of age. Previous studies have shown that bmi changes significantly during this period, which is important for later obesity. Generally speaking, after this period, a child’s body mass index rises steadily until early adulthood. Body mass index (bmi) is a common standard used internationally to measure the degree of obesity and health status of human body.

To find out why, the team from imperial college London, the university of surrey and the university of oulu in Finland analysed the body mass index and other indicators of more than 22,000 young children and compared their genetic make-up.


The published in the new issue of the journal science progress of the research results showed that although a body mass index (bmi) and infant stage related to a unique set of genetic variations have little impact on weight change in the future, but some gene variants are associated with adult body mass index (4 to 7 years old) in preschool period began to play a role.

One of the report’s authors, professor mario-rita yerwelyn of imperial college London, said there were nearly 100 genetic variants that increase a person’s risk of obesity as an adult, and these variants appeared to be active as early as the age of about four.