The shell is a by-product of the coffee production process and is often used as fertilizer, among other things. A new study in the United States has found that extracts from coffee bean shells can reduce obesity-related inflammation in mice and increase insulin sensitivity.
Researchers at the university of Illinois, the United States led the team from coffee bean shell and fall off after roasting “silver skin” protocatechuic acid and gallic acid extracted two phenolic substances, and use these materials to deal with the fat cells in mice, macrophages of mice and fat cells and related hormone changes, and the reaction of inflammatory pathways.
Previous studies have found chronic inflammation in the abdominal fat tissue of severely overweight people, which is often cited as a factor in changes in insulin levels, type 2 diabetes and even an increased risk of cancer in obese people.
The newly published in the British journal of chemical and food toxicology research shows that when there is an obesity related to inflammation, interaction between macrophages and fat cells, fat cells within the mitochondria decreased, fat burning, a decrease in the ability of oxidative stress level, so as to interfere with the absorption of glucose, metabolic rate slows. Phenols extracted from coffee bean shells can block the effect of macrophages on fat cells, maintain the ability of fat burning, stimulate the decomposition of fat, stimulate the sensitivity of the insulin pathway, promote the uptake and utilization of glucose, and restore normal metabolism.
The discovery could lead to new treatments for type 2 diabetes and cardiovascular disease, as well as potential business opportunities for coffee bean shells, the researchers said.